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10.1067/mai.2002.126780 J Allergy Clin Immunol

doi: 10.1038/nature04330 135 GarrutiGDe FazioMCapuanoPMartinezGRotelliMTPuglisiFet al

PLoS One 9: e110948

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When examining the crystal structure of the SmTGRNADPH complex (PDB 2X99) one can see that the Y296 residue is found in a conformation stacked with the NADPH nicotinamide that is roughly parallel to the flavin

Quercetin has been reported to attenuate Th2-mediated inflammation in MC903-induced AD mouse model along with reduced expression of CCL17 and CCL22, which may contribute to reduced Th2 cell infiltration